Saucony Guide 10 vs. ASICS GEL-Kayano 24 review

Saucony Guide 10 provides a very cushy, smooth, and comfortable ride to overpronators. ASICS GEL-Kayano 24 provides softness, comfort, and a touch of stability to overpronators.

NEW! Saucony Guide ISO vs. ASICS GEL-Kayano 25

The Saucony Guide 10 and the ASICS GEL-Kayano 24 are stability running shoes for moderate overpronators.


The uppers of the Saucony Guide 10 The preceding link takes you to and the ASICS GEL-Kayano 24 are quite similar in that they consist of engineered mesh and no-sew overlays.

However, the Saucony Guide 10 has more overlays in its upper than the ASICS GEL-Kayano 24, which comes with some underlays for additional support.

The ASICS GEL-Kayano 24 The preceding link takes you to depends mostly on the mesh, some underlays, and the logo on the lateral side to provide support in the midfoot and forefoot areas.

However, the ASICS GEL-Kayano 24 increases the amount of support at the back by using a sturdy external heel counter that extends toward the midfoot and thus helps to reduce heel rotation.

The Saucony Guide 10 does not come with an external heel counter, but you should still be able to get enough support at the back.

All in all, you might get an overall more secure fit from the Saucony Guide 10, and the ASICS GEL-Kayano 24 provides more support toward the back of the running shoe.

Both the Saucony Guide 10 and the ASICS GEL-Kayano 24 are meant to give runners a soft ride. However, they use different midsole technologies to do so.

The midsole of the ASICS GEL-Kayano 24 consists of two layers of foam with GEL cushioning between the two layers.

The layer that is closest to the ground is a somewhat firmer and responsive layer, while the upper layer closest to the foot is somewhat softer.

The Saucony Guide 10 has one main layer of foam in its midsole but comes with a top layer of softer foam.

The Saucony Guide 10 has a landing zone that is built into the midsole under the heel, and it provides more ground contact than the ASICS GEL-Kayano 24.


Running shoe lab tests show that the Saucony Guide 10 provides almost a maximum amount of forefoot cushioning to both men and women so outcushions the ASICS GEL-Kayano 24 in that area.

The Saucony Guide 10 also provides almost a maximum amount of heel cushioning to men but somewhat less to women.

Because the heel of the ASICS GEL-Kayano 24 for women comes with 3 mm of extra height in the heel, the ASICS GEL-Kayano 24 is likely to provide more heel cushioning to women than the Saucony Guide 10.

Both the ASICS GEL-Kayano 24 and the Saucony Guide 10 come with a support system on the medial side of their midsoles.

The Saucony Guide 10 comes with a long medial post that runs high up, so it provides quite a bit a support to overpronators, and according to running shoe lab tests, more support than the ASICS GEL-Kayano 24 does.

The ASICS GEL-Kayano 24 is also listed by ASICS as a running shoe that can be worn by neutral runners, so the amount of stability and support it provides is mild to moderate.

The Saucony Guide 10 does not come with a midfoot shank like the ASICS GEL-Kayano 24, but rather provides full ground contact under the midfoot, which not only increases the amount of support you get but also increases the smoothness of your ride from heel to toe.

The women's version of the ASICS GEL-Kayano 24 weighs approximately 9.3 oz (264 grams), and the Saucony Guide 10 for women weighs 8.4 oz (238 grams).

The men's versions of the shoes weigh 11.3 oz (320 grams) and 10.1 oz (286 grams), respectively, with the Saucony Guide 10 being the lighter one.

If you are a mild to moderate overpronator who is looking for a soft ride, you could choose either the ASICS GEL-Kayano 24 or the Saucony Guide 10.

If you need quite a bit of stability and support, you may want to consider the Saucony Guide 10 more than the ASICS GEL-Kayano 24.

Note: The weight of a running shoe depends on the size of the running shoe, so any weights mentioned in this review may differ from the weight of the running shoe you choose to wear. Running shoes of the same size were compared for this review.

The two links above will take you to where you can read more about the running shoes.

Disclaimer: This running shoe review on is based on personal research and analysis of data that has been made publicly available by running shoe manufacturers and other companies that are dedicated to serving runners, and is not claimed to be accurate, complete, or up to date. While the information presented in this review is intended to help you better understand the differences between running shoes, we shall not be held liable for any purchasing decisions you make based on this information. Please use your own good judgment before making a purchase. The owner of this website receives a small compensation whenever you buy a product after clicking a product link on this website. Read our full disclaimer and privacy policy.